Faculty Biography

Bindong Liu headshot

Bindong Liu, PhD

Professor
Microbiology, Immunology, Physiology
School of Medicine
(615) 327-6877 | bliu@mmc.edu

Center Affiliations

Center for AIDS Health Disparities Research

Research Themes

Infectious Diseases

Active Research Projects

DoD: Developing a High Efficient Gene-Editing Tool to Edit the Human APOBEC3G Gene in HSC for Improving HIV-1 Treatment

NIH: Characterizing a small molecule of Streptococcus cristatus for HIV drug design

NIH: The RCMI Program in Health Disparities Research at Meharry Medical College, FACS/ BSL3 Core Facility

NIH: Tennessee Center for AIDS Research, Laboratory Science Core

Publications

Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.
Jing Liu, Amrita Banerjee, Charles A Herring, Jonathan Attalla, Ruiying Hu, Yanwen Xu, Qiujia Shao, Alan J Simmons, Prasanna K Dadi, Sui Wang, David A Jacobson, Bindong Liu, Emily Hodges, Ken S Lau, Guoqiang Gu

Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV.
Xin-Hong Dong, Meng-Hsuan Ho, Bindong Liu, James Hildreth, Chandravanu Dash, J Shawn Goodwin, Muthukumar Balasubramaniam, Chin-Ho Chen, Hua Xie

Differential Contributions of Ubiquitin-Modified APOBEC3G Lysine Residues to HIV-1 Vif-Induced Degradation.
Tiffany Turner, Qiujia Shao, Weiran Wang, Yudi Wang, Chenliang Wang, Ballington Kinlock, Bindong Liu

GB virus type C E2 protein inhibits human immunodeficiency virus type 1 Gag assembly by downregulating human ADP-ribosylation factor 1.
Chenliang Wang, Christine L Timmons, Qiujia Shao, Ballington L Kinlock, Tiffany M Turner, Aikichi Iwamoto, Hui Zhang, Huanliang Liu, Bindong Liu

HIV-1 Vif inhibits G to A hypermutations catalyzed by virus-encapsidated APOBEC3G to maintain HIV-1 infectivity.
Yudi Wang, Ballington L Kinlock, Qiujia Shao, Tiffany M Turner, Bindong Liu

Heat-stable molecule derived from Streptococcus cristatus induces APOBEC3 expression and inhibits HIV-1 replication.
Ziqing Wang, Yi Luo, Qiujia Shao, Ballington L Kinlock, Chenliang Wang, James E K Hildreth, Hua Xie, Bindong Liu


Keywords

HIV-1, antiviral, viral-host interaction, host restriction factor, small molecule

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